The Danish painter Einar Wegener and his wife, the painter Gerda, lead an eventful artistic life in Copenhagen in the 1920s. One day, when Gerda asks her husband to have himself painted dressed as a woman, she has no idea what she is about to unleash. For Einar feels exceptionally comfortable as a woman. He increasingly slips into the role of "Lili", in which he discovers his true identity. His desire to be able to live completely as a woman through a sex change grows.

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